PHA-767491 Washing

PHA-767491 WashingPHA 767491 is a potent ATP competitive dual Cdc7 CDK9 inhibitor with IC50 of 10 nM and 34 nM in cell free assays, respectively. It displays ~20 fold selectivity against CDK1 2 and GSK3 ?, 50 fold selectivity against MK2 and CDK5, 100 fold selectivity against PLK1 and CHK2.

and also act as an inhibitor of sirtuins

certified nonpyrogenic and DNase-/RNase-free 95 k PA (14psi) pressure tested - COP

Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays

Corning These 10mL PYREX® graduated cylinders are calibrated "to contain" (TC) and have a funnel top

It is more selective for CDK1

with IC50 of 80 nM and 2 nM in cell-free assays

Corning The red Corning® open top polybutylene terephthalate (PBT) high temperature caps have a GL45 thread and are designed to be used with piercible silicone septa (sold separately

this fiber glass contains minimal heavy metals and is suitable for use as a filtering medium

compared to CDKs

Corning 100mm Style Tissue Culture-Treated Culture Dishes

83 nM in a cell-free assay

25-fold greater selectivity against MKK3